Thelma Pickles was born in 1941 in Liverpool, England. In 1951, her father left her and her family.
"My father had left me when I was ten. Because of that, I had a huge chip on my shoulder. In those days, you never admitted you came from a broken home. You could never discuss it with anybody and people like me, who kept the shame of it secret, developed terrific anxieties."

In 1957, Thelma Pickles entered Liverpool College of Art. Helen Anderson introduced her to John Lennon. John was sitting on the "signing in" table in front of the collage with Tony Carricker.

"My eyes definitely set on John. Tony was prettier, more handsome, with dark hair and dark eyes, but John was so powerful. When he was in a group like that, the focus of attention went to him. He had a presence. I found him very striking from that moment on"

Thelma`s and John`s friendship blossomed when they were in no hurry to go home and sat on the steps of the Queen Victoria monument for a talk near the bus terminal. During this time, John started calling her "Thel." In February of 1958, John and Thelma became a couple, becoming close by the understanding of broken families.

"Most people stopped short. They were probably frightened of him, and on occasions, there were certainly fights. But with me, he met someone with almost the same background."

At first, Thelma believed that John didn`t care about his father`s leaving, but later realized that he did care.

"As I got to know him, he obviously cared. But what I realized quickly was that he and I had an aggression towards life that stemmed entirely from our messy home lives."

John and Thelma both had a rebellious streak. John`s Aunt Mimi Smith hated his tight trousers while Thelma`s mother hated her black stockings. John and Thelma would sag off college in the afternoons to see films and would hang out at Ye Cracke bar with other students. In July of 1958, John`s mother, Julia, got killed in a car accident, sending John into a tailspin. One night, John rounded on Thelma in front of several students and was rude to her.
"Don`t blame me, just because your mother`s dead!" was her response. John went quiet and things came to a turning point, with him now respecting her, after she responded to his viciousness with a sentence that was equally offensive. When together, the affinity was special with a particular emphasis on sick humor.

"John laughed and ran up to them [the elderly and/or disabled] to make horrible faces. I laughed with him while feeling awful about it. If a doddery old person had nearly fallen over because John had screamed at her, we`d be laughing. We knew it shouldn`t be done. I was a good audience, but he didn`t do it for my benefit. Children often find that kind of sick humor amusing. Perhaps we just hadn`t grown out of it. He would pull the most grotesque faces and try to imitate his victims."

On the nights when John`s Aunt Mimi Smith was due to go out for the evening for bridge, John and Thelma would meet on a seat in a brick-built shelter on the golf course. When the coast was clear, they would go inside the house to spend some more quality time together. Well aware of John`s failing in their art classes, Thelma would write fake papers for him so that he wouldn`t fail in lettering. By July of 1958, John was growing attracted to another student, Cynthia Powell.

"I was in his camp of boys because I was a bit of an arty beatnik.