He co-directed Bruce Springsteen's "Streets Of Philadelphia" music video.

Uncle of Ted Demme.

He frequently casts the same actors in most of his films, including Paul Lazar, Ted Levine, Harry Northup, Charles Napier, Dean Stockwell, Robert W. Castle, Denzel Washington, Jude Ciccolella, and Tracey Walter. He also tends to use non-actor friends or musicians he likes, as long as they are "interesting".

Directed Bruce Springsteen's "Murder Incorporated" music video (1995).

Directed 7 different actors in Oscar-nominated performances: Mary Steenburgen, Jason Robards, Christine Lahti, Dean Stockwell, Anthony Hopkins, Jodie Foster and Tom Hanks. Steenburgen, Hopkins, Foster and Hanks won Oscars for their performances in one of Demme's movies.

Father of Josephine Demme.

Awarded honorary degree by Wesleyan University (June 3, 1990).

Has 3 children, with wife Joanne Howard.

Frequently uses Pablo Ferro for his Title Sequences and montages.

Was voted the 45th Greatest Director of all time by Entertainment Weekly.

He and Michael Mann have both directed a Hannibal Lecter film and have also both been involved in a film about Howard Hughes. Mann directed Manhunter (1986) and produced The Aviator (2004), which he was originally to have directed. One of Demme's earliest films was Melvin and Howard (1980), and he later went on to direct _Silence of the Lambs, The (1991)_.

Biography in: John Wakeman, editor. "World Film Directors, Volume Two, 1945-1985". Pages 255-258. New York: The H.W. Wilson Company, 1988.

Member of jury at the Cannes Film Festival in 2000