They have a son named Sky Cole age 5.
On November 1, 2003, Berkley married artist and occasional actor Greg Lauren at the Esperanza Hotel in Cabo San Lucas. Berkley formally changed her name to Elizabeth Berkley Lauren, however, she still uses her maiden name professionally. On March 5, 2012, Berkley announced she was expecting her first child in the summer. On July 20, 2012, son Sky Cole was born. Berkley gave birth just 8 days before her 40th birthday.