(August 20, 1989 - October 1, 1995) (divorced)
Thompson's first husband was the actor and director Kenneth Branagh, whom she met in 1987 while filming the television series Fortunes of War. The couple married in 1989 and proceeded to appear in several films together, with Branagh often casting her in his own productions. Dubbed a "golden couple" by the British media, the relationship received considerable press interest. The pair attempted to keep their relationship private, refusing to be interviewed or photographed together. In September 1995, Thompson and Branagh announced that they had separated; their statement to the press blamed their work schedules, but it later emerged that he had fallen in love with actress Helena Bonham Carter.
Thompson was living alone as the relationship with Branagh deteriorated, and entered into clinical depression.