In 1948, he met then-unknown actress and model Marilyn Monroe when she was being photographed by Hollywood pin-up photographer Bruno Bernard at the Racquet Club of Palm Springs. Taking her on as a client, he had her undergo minor plastic surgery, and used his influence to help her land the roles of Angela in The Asphalt Jungle and Miss Caswell in All About Eve. The buzz generated by her performances enabled Hyde to negotiate a contract for Monroe with 20th Century Fox.
Despite the fact that Monroe was nearly 31 years his junior, Hyde eventually left his wife for her. He wanted to marry her, but she repeatedly refused; she said she loved Hyde, but was not in love with him.