(August 13, 1943 - June 14, 2007) (her death) (5 children)
On August 13, 1943, Graham married Wheaton classmate Ruth Bell (1920–2007), whose parents were Presbyterian missionaries in China. Her father, L. Nelson Bell, was a general surgeon. Ruth Graham died on June 14, 2007, at the age of 87. The Grahams were married for almost 64 years.
Graham and his wife had five children together: Virginia Leftwich (Gigi) Graham (born 1945; an inspirational speaker and author); Anne Graham Lotz (born 1948; runs AnGeL ministries); Ruth Graham (born 1950; founder and president of Ruth Graham & Friends, leads conferences throughout the U.S. and Canada); Franklin Graham (born 1952, who serves as president and CEO of the Billy Graham Evangelistic Association and as president and CEO of international relief organization, Samaritan's Purse); and Nelson Edman Graham (born 1958; a pastor who runs East Gates Ministries International, which distributes Christian literature in China).
Graham has 19 grandchildren and numerous great-grandchildren. His grandson Tullian Tchividjian, son of Gigi, was the senior pastor of Coral Ridge Presbyterian Church in Fort Lauderdale, Florida until he was defrocked in June 2015 after admitting to an extra-marital affair. Tchividjian later filed for divorce from his wife, Kim. Grandson Basyle "Boz" Tchividjian, a former child abuse chief prosecutor and professor at Liberty University School of Law, is the founder and executive director of Godly Response to Abuse in the Christian Environment, a nonprofit dedicated to preventing and responding to abuse in Christian organizations.