Ryan Grigson (born February 23, 1972) is the general manager for the Indianapolis Colts of the National Football League (NFL). He played college football as a tight end and offensive tackle for the Purdue Boilermakers. He was drafted by the Cincinnati Bengals in the sixth round of the 1995 NFL Draft. He was a member of the Detroit Lions from 1995–1996, and played for the Toronto Argonauts of the Canadian Football League in 1997 before he retired due to a back injury. Grigson was a pro scout for the Saskatchewan Roughriders and an assistant coach for McPherson College in 1998. In 1999 he was a player personnel coordinator and assistant coach for the Buffalo Destroyers of the Arena Football League. From 1999 to 2003, Grigson was a national and regional scout for the St. Louis Rams. He was hired by the Eagles as a western regional scout in 2004, and was promoted to director of college scouting in 2006. He was promoted to director of player personnel in 2010 before being hired by the Colts in 2012.