Patrick Dempsey (as Ronald Miller) with Darcy Demoss (as Patty)
in Can`t Buy Me Love (1987)

Patrick Dempsey (as Ronald Miller) with Amanda Peterson (as Cindy Mancini)
in Can`t Buy Me Love (1987)

Patrick Dempsey (as Ronald Miller) with Tina Caspary
in Can`t Buy Me Love (1987)

Patrick Dempsey (as Ronald Miller) with Devin De Vasquez
in Can`t Buy Me Love (1987)

Patrick Dempsey (as Ellsworth 'Sonny' Wisecarver) with Beverly D`Angelo (as Francine Glatt)
in In the Mood (1987)

Patrick Dempsey (as Ellsworth 'Sonny' Wisecarver) with Talia Balsam (as Judy Cusimano)
in In the Mood (1987)

Patrick Dempsey (as Michael) with Jennifer Connelly (as Gabriella D'Arc)
in Some Girls (1988)

Patrick Dempsey (as Randy Bodek) with Nancy Valen (as Jenny Gordon)
in Loverboy (1989)

Patrick Dempsey (as Christopher Wooden) with Helen Slater (as Alexandra Page)
in Happy Together (1989)

Patrick Dempsey (as Charlie Farrow) with Kelly Preston (as Karen Landers)
in Run (1991)

Patrick Dempsey (as Charlie Hunter) with Molly Ringwald (as Lisa Hunter)
in Face the Music (1993)

Patrick Dempsey (as Matthew) with Eric McCormack (as Will Truman)
in Will & Grace (1998)

Patrick Dempsey (as Andrew Hennings) with Reese Witherspoon (as Melanie Smooter)
in Sweet Home Alabama (2002)

Patrick Dempsey (as Dr. Derek Shepherd) with Ellen Pompeo (as Dr. Meredith Grey)
in Grey`s Anatomy (2005)

Patrick Dempsey (as Dr. Derek Shepherd) with Kate Walsh (as Dr. Addison Montgomery-Shepherd)
in Grey`s Anatomy (2005)

Patrick Dempsey (as Scott Casey) with Hilary Swank (as Erin Gruwell)
in Freedom Writers (2007)

Patrick Dempsey (as Robert Philip) with Amy Adams (as Giselle)
in Enchanted (2007)

Patrick Dempsey (as Tom) with Michelle Monaghan (as Hannah)
in Made of Honor (2008)

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