| Oddballs | 2022 | Grandma | TV Show |
| The Great North | 2021 | Aunt Dirt | TV Show |
| Q-Force | 2021 | Judy | TV Show |
| Harriet the Spy | 2021 | Ole Golly / Robot Ole Golly | TV Show |
| Only Murders in the Building | 2021 | Sazz Pataki | TV Show |
| The Ghost and Molly McGee | 2021 | Ms. Roop | TV Show |
| The Bystanders | 2021 | The Narrator | TV Show |
| Hot White Heist | 2021 | Brenda | TV Show |
| Glitch Techs | 2020 | Joan Fishback | TV Show |
| Solar Opposites | 2020 | Kabronius | TV Show |
| Space Force | 2020 | Admiral Mayweather | TV Show |
| 100% Wolf | 2020 | The Commander (voice) | Movie |
| Close Enough | 2020 | Barb | TV Show |
| Spirit Riding Free: Riding Academy | 2020 | Coach Bradley | TV Show |
| The Chicken Squad | 2020 | Dr. Dirt | TV Show |
| Sarah Cooper: Everything's Fine | 2020 | KJ Dillard | TV Show |
| Carcerem | 2020 | Mel | TV Show |
| Bitmoji TV | 2020 | | TV Show |
| UglyDolls | 2019 | Scanner / Electronic Female Voice (voice) | Movie |
| Archibald's Next Big Thing | 2019 | Sorry Culpepper | TV Show |
| Middle School Moguls | 2019 | Mogul Victoria | TV Show |
| Tuca & Bertie | 2019 | Meredith Maple | TV Show |
| Ralph Breaks the Internet | 2018 | Calhoun (voice) | Movie |
| Final Space | 2018 | AVA / Dartricio / Mrs. Graven / ... | TV Show |
| Dallas & Robo | 2018 | Carol / Carol The Biker King | TV Show |
| Summer Camp Island | 2018 | Skadi's Mom / Additional Voices | TV Show |
| Blark and Son | 2018 | Frankie | TV Show |
| The Birds Sing Too Loud | 2018 | Clarice | Short Film |
| A Play | 2018 | Betty | Short Film |
| Dropping the Soap | 2017 | Olivia Vanderstein | TV Show |
| Little Bird's Big Adventure | 2017 | Olga (voice) | Movie |
| Manhunt | 2017 | Janet Reno | TV Show |
| The Good Fight | 2017 | Madeline Starkey | TV Show |
| Big Hero 6: The Series | 2017 | Supersonic Sue | TV Show |
| The Marvelous Mrs. Maisel | 2017 | Sophie Lennon | TV Show |
| Relatively Happy | 2017 | Bobbi Martin | TV Movie |
| Ryan Hansen Solves Crimes on Television | 2017 | Jane Lynch | TV Show |
| Your Biggest Fan | 2017 | | TV Show |
| The Late Bloomer | 2016 | Caroline Chambers | Movie |
| After the Reality | 2016 | Doctor | Movie |
| Angel from Hell | 2016 | Amy | TV Show |
| The Real O'Neals | 2016 | Jane Lynch | TV Show |
| Writer's Block | 2016 | Jane | Short Film |
| Mascots | 2016 | Gabby Monkhouse | Movie |
| Tween Fest | 2016 | Sophia Sharp | TV Show |
| The Adventures of Puss in Boots | 2015 | Sally | TV Show |
| The Stinky & Dirty Show | 2015 | Dumper | TV Show |
| Goldie and Bear | 2015 | Mrs. Locks | TV Show |
| The Mr. Peabody & Sherman Show | 2015 | Bernadette Steele | TV Show |
| The Team Unicorn Saturday Action Fun Hour! | 2014 | Dark Puba | TV Show |
| We Bare Bears | 2014 | Tank / Additional Voices | TV Show |
| The Loud House | 2014 | Coach Hutch | TV Show |
| A.C.O.D. | 2013 | Dr. Judith | Movie |
| Afternoon Delight | 2013 | Dr. Lenore | Movie |
| Murder Police | 2013 | | TV Show |
| Jane Lynch in Wrong Tracks | 2013 | | Short Film |
| Jungle Master | 2013 | Ilene (English version, voice) | Movie |
| Delhi Safari | 2012 | Female Flamingo (English version, voice) | Movie |
| Escape from Planet Earth | 2012 | Io (voice) | Movie |
| The Three Stooges | 2012 | Mother Superior | Movie |
| Dino Time | 2012 | Sue (voice) | Movie |
| Wreck-It Ralph | 2012 | Calhoun (voice) | Movie |
| The High Fructose Adventures of Annoying Orange | 2012 | Cobb / Jane the Peanut | TV Show |
| 8 | 2012 | Maggie Gallagher | TV Movie |
| Abominable Christmas | 2012 | Margaret Knowhow (voice) | TV Movie |
| Wreck-It Ralph | 2012 | Sergeant Calhoun (voice) | Unknown |
| Paul | 2011 | Pat Stevens | Movie |
| Bubble Guppies | 2011 | Genie | TV Show |
| Rio | 2011 | Alice (The Other Goose) (voice) | Movie |
| Bob's Burgers | 2011 | Carol | TV Show |
| Portlandia | 2011 | Barbecue Planner | TV Show |
| Carpool | 2011 | | Short Film |
| Web Therapy | 2011 | Claire Dudek | TV Show |
| Small Fry | 2011 | Neptuna (voice) | Short Film |
| Mitzvah Communion | 2011 | Elaine French | Short Film |
| Shrek Forever After | 2010 | Gretched (voice) | Movie |
| Neighbors from Hell | 2010 | Alex | TV Show |
| Marvel Super Hero Squad: The Infinity Gauntlet | 2010 | Nebula (voice) | Unknown |
| Pretty Parts | 2010 | | Short Film |
| Glee Cast Feat. Olivia Newton-John: Physical | 2010 | Sue Sylvester | Music Video |
| Ice Age: Dawn of the Dinosaurs | 2009 | Diatryma Mom (voice) | Movie |
| Julie & Julia | 2009 | Dorothy McWilliams | Movie |
| Free Birds | 2009 | Rosie (voice) | Movie |
| Spring Breakdown | 2009 | Senator 'Kay Bee' Hartmann | Movie |
| Post Grad | 2009 | Carmella Malby | Movie |
| Weather Girl | 2009 | J.D. | Movie |
| Party Down | 2009 | Constance Carmell | TV Show |
| The Cleveland Show | 2009 | Sue Sylvester / Ms. Eck | TV Show |
| Glee | 2009 | Sue Sylvester / Jane Lynch / Will Schuester | TV Show |
| Mr. Troop Mom | 2009 | Miss Hulka | TV Movie |
| The Super Hero Squad Show | 2009 | Nebula | TV Show |
| Big Breaks | 2009 | M.J. | Short Film |
| Glee: Director's Cut Pilot Episode | 2009 | Sue Sylvester | TV Movie |
| Adventures of Power | 2008 | Joni | Movie |
| Another Cinderella Story | 2008 | Dominique | TV Movie |
| Role Models | 2008 | Sweeny | Movie |
| Man Maid | 2008 | Lonely Businesswoman | Movie |
| Space Chimps | 2008 | Dr. Poole (voice) | Movie |
| The Rocker | 2008 | Lisa | Movie |
| The Toe Tactic | 2008 | Honey Strumpet | Movie |
| Tru Loved | 2008 | Ms. Maple | Movie |
| The Spectacular Spider-Man | 2008 | Joan Jameson | TV Show |
| Leisure Suit Larry: Box Office Bust | 2008 | Denise Lemon (voice) | Unknown |
| Never Better | 2008 | Linda | TV Movie |
| Easy to Assemble | 2008 | Manager Swenka / Manager Gjorna | TV Show |
| Web Therapy | 2008 | Claire Dudek | TV Show |
| Alex's Halloween | 2008 | Mother | Short Film |
| The Adventures of Captain Cross Dresser | 2008 | | TV Show |
| The Consultants | 2008 | Chase | TV Movie |
| Alvin and the Chipmunks | 2007 | Gail | Movie |
| I Do & I Don't | 2007 | Nora Stelmack | Movie |
| Smiley Face | 2007 | Casting Director | Movie |
| Suffering Man's Charity | 2007 | Ingrid Sorensen | Movie |
| The Hammer | 2007 | Woman Who Argues With Jerry (uncredited) | Movie |
| The List | 2007 | Dr. Davina | Movie |
| Walk Hard: The Dewey Cox Story | 2007 | Gail the Television Reporter | Movie |
| Love Is Love | 2007 | Reverend Greeley | Short Film |
| Area 57 | 2007 | Irene Maloof | TV Movie |
| Untitled Christine Taylor Project | 2007 | Janet | TV Movie |
| iCarly | 2007 | Pam Puckett | TV Show |
| Phineas and Ferb | 2007 | Mrs. Johnson / Additional Voices | TV Show |
| WordGirl | 2007 | | TV Show |
| Eye of the Dolphin | 2006 | Elizabeth | Movie |
| Fifty Pills | 2006 | Doreen | Movie |
| For Your Consideration | 2006 | Cindy | Movie |
| Talladega Nights: The Ballad of Ricky Bobby | 2006 | Lucy Bobby | Movie |
| The Frank Anderson | 2006 | Dr. Emily Brice | Short Film |
| Separated at Worth | 2006 | Jennifer | TV Movie |
| Campus Ladies | 2006 | Professor | TV Show |
| Handy Manny | 2006 | Jackie Greenway | TV Show |
| Help Me Help You | 2006 | Raquel Janes | TV Show |
| Lovespring International | 2006 | Victoria Ratchford | TV Show |
| Psych | 2006 | Commander Barbara Dunlap | TV Show |
| The New Adventures of Old Christine | 2006 | Ms. Hammond | TV Show |
| Bam Bam and Celeste | 2005 | Darlene | Movie |
| The 40-Year-Old Virgin | 2005 | Paula | Movie |
| The Californians | 2005 | Sybill Platt | Movie |
| Promtroversy | 2005 | Mimi Nimby (Concerned Parent) | Short Film |
| American Dad! | 2005 | Mother / Angry Woman / Mother (Farmer's Wife) / ... | TV Show |
| Blind Justice | 2005 | Dr. Taylor | TV Show |
| Criminal Minds | 2005 | Diana Reid | TV Show |
| Illeanarama | 2005 | Ann | TV Show |
| My Name Is Earl | 2005 | Sissy | TV Show |
| Night Stalker | 2005 | Dr. Dominic Messinger | TV Show |
| The Life and Times of Juniper Lee | 2005 | Madame Rothchild | TV Show |
| Unscripted | 2005 | Jane | TV Show |
| Weeds | 2005 | The Candyman | TV Show |
| Holly Hobbie and Friends: Surprise Party | 2005 | Joan Hobbie / Minnie | TV Show |
| A Series of Unfortunate Events | 2004 | Realtor (uncredited) | Movie |
| Sleepover | 2004 | Gabby | Movie |
| Surviving Eden | 2004 | Maude Silver | Movie |
| Little Black Boot | 2004 | Grace | Short Film |
| Memoirs of an Evil Stepmother | 2004 | Blanche Monroe | Short Film |
| Boston Legal | 2004 | Joanna Monroe | TV Show |
| Desperate Housewives | 2004 | Maxine Bennett | TV Show |
| Father of the Pride | 2004 | Lily / Gift Store Clerk | TV Show |
| Rodney | 2004 | Amy O'Brien | TV Show |
| The L Word | 2004 | Joyce Wischnia | TV Show |
| Veronica Mars | 2004 | Mrs. Donaldson | TV Show |
| How to Be a Hollywood Player in Less Than Ten Minutes | 2004 | Hollywood Mogul | Short Film |
| A Mighty Wind | 2003 | Laurie Bohner | Movie |
| Exposed | 2003 | Julie Gross | Movie |
| Arrested Development | 2003 | Cindi Lightballoon | TV Show |
| Las Vegas | 2003 | Helen Putasca | TV Show |
| Reno 911! | 2003 | Therapist | TV Show |
| Spider-Man | 2003 | Oscorp Executive | TV Show |
| Two and a Half Men | 2003 | Dr. Linda Freeman | TV Show |
| Collateral Damage | 2002 | FBI Agent Russo | Movie |
| The Big Time | 2002 | Miss Rush | TV Movie |
| MDs | 2002 | Aileen Poole, RN, Ph.D | TV Show |
| Monk | 2002 | Dr. Julie Waterford | TV Show |
| The Dead Zone | 2002 | Flo McMurtry | TV Show |
| Watching Ellie | 2002 | Roman | TV Show |
| Nice Guys Finish Last | 2001 | Mom | Short Film |
| According to Jim | 2001 | Janice | TV Show |
| Robot Chicken | 2001 | Miss Grundy | TV Show |
| The Division | 2001 | | TV Show |
| Martini | 2001 | Dr. Jane | Short Film |
| Best in Show | 2000 | Christy Cummings | Movie |
| Red Lipstick | 2000 | Final TV Newscaster | Movie |
| What Planet Are You From? | 2000 | Doreen | Movie |
| Boston Public | 2000 | Jane Morrell | TV Show |
| CSI: Crime Scene Investigation | 2000 | Ranger | TV Show |
| Gilmore Girls | 2000 | Nurse | TV Show |
| The Weber Show | 2000 | Carla | TV Show |
| Titus | 2000 | Prosecutor | TV Show |
| Color Me Gay | 2000 | Executive | Short Film |
| Family Guy | 1999 | Dotty Campbell / Patsy Ramsey / French Teacher | TV Show |
| Family Law | 1999 | Cheryl Bowman | TV Show |
| Judging Amy | 1999 | ASA Perkins | TV Show |
| Popular | 1999 | Suzi Klein | TV Show |
| The West Wing | 1999 | Reporter in Briefing Room / Reporter | TV Show |
| Dawson's Creek | 1998 | Mrs. Witter | TV Show |
| Felicity | 1998 | Professor Carnes | TV Show |
| The King of Queens | 1998 | Dr. Foreman | TV Show |
| Will & Grace | 1998 | Roberta | TV Show |
| Touch Me | 1997 | Counselor | Movie |
| Dharma & Greg | 1997 | Sheryl | TV Show |
| 3rd Rock from the Sun | 1996 | Ms. Koppel | TV Show |
| 7th Heaven | 1996 | Nurse | TV Show |
| Arli$$ | 1996 | | TV Show |
| Arthur | 1996 | Patty Ratburn | TV Show |
| Caroline in the City | 1995 | Hostess | TV Show |
| Cybill | 1995 | Mrs. Sweeney | TV Show |
| In the House | 1995 | Ruth | TV Show |
| JAG | 1995 | Sandy's Friend | TV Show |
| NewsRadio | 1995 | Carol | TV Show |
| Friends | 1994 | Ellen | TV Show |
| Party of Five | 1994 | Dr. Pennant | TV Show |
| Fatal Instinct | 1993 | Prison Reporter | Movie |
| The Fugitive | 1993 | Doctor Kathy Wahlund | Movie |
| Bakersfield P.D. | 1993 | Michelle Hathaway | TV Show |
| Frasier | 1993 | Cynthia | TV Show |
| NYPD Blue | 1993 | Susanna Howe | TV Show |
| The John Larroquette Show | 1993 | Mary Travers | TV Show |
| The X-Files | 1993 | Mrs. Anne T. Lokensgard | TV Show |
| Joe's Life | 1993 | Saleswoman | TV Show |
| Straight Talk | 1992 | Gladys (voice) | Movie |
| In the Best Interest of the Children | 1992 | Gwen Hatcher (as Jany Lynch) | TV Movie |
| The Simpsons | 1989 | Jeanie / Roz Davis | TV Show |
| Vice Versa | 1988 | Ms. Lindstrom | Movie |
| Empty Nest | 1988 | Tammy | TV Show |
| Married... with Children | 1987 | Greta | TV Show |
| Echo Planet | | | Movie |
| Fairy Tale Forest | | Sinistra | TV Movie |
| The Bravest Knight | | Lug Lug | TV Show |
| Bucktown | | | TV Show |
| Ridley Jones | | Lonny | TV Show |
| El Deafo | | Mrs. Sinkleman | TV Show |
| Animals | | | TV Show |
