Colin Nichols

Colin Nichols
Colin Nichols  
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Colin Nichols is a member of the following lists: British expatriates in the United States, Alumni of the University of Leeds and British scientist stubs.

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Official Websites http://nicholslab.wustl.edu

Colin Nichols is distinguished for his contributions to our understanding of cellular excitability and its role in disease. He was instrumental in cloning the first inward rectifier channel and the regulatory subunit of the KATP channel. He elucidated the mechanism of inward rectification, generated new insights into lipid regulation of ion channel function, determined the physiological role of cardiac KATP channels and identified one type of congenital hyperinsulinism. Animal models that he generated predicted the mechanism of human neonatal diabetes, and ultimately helped enable patients to switch from insulin injections to oral drug therapy.

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