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Despina Khatun is a member of the following lists: Iranian Christians, 15th-century births and Queens consort of Persia.
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Theodora Megale Komnene (Greek: Θεοδώρα Μεγάλη Κομνηνή), also known as Despina Khatun (Persian: دسپینا خاتون; from the Greek title despoina and Turco-Mongol title khatun, both meaning "lady"), was the daughter of John IV of Trebizond and his wife Bagrationi, a daughter of King Alexander I of Georgia. She married the Aq Qoyunlu ruler Uzun Hasan in 1458. She became the mother of Halima Alamshah Hatun who became the mother of first Safavid king, Shah Ismail I.
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