In 1322 Elisenda became the fourth and last wife of James II of Aragon, thirty years her senior. Elisenda became stepmother to James' ten children by his second marriage to Blanche of Naples. The marriage lasted for only five years before James died in November 1327, they had no children.
A year after she was widowed, she retired to the monastery of Pedralbes palace immediately. Although she was never a nun, she was endowed with wide powers over the internal workings of the monastery. Elisenda remained there for the rest of her life.