Has 3 children (daughters: Charlotte Wiseman and Taran Wiseman, son: Andreas Wiseman - a.k.a. Rainbow) from a long relationship, with Patrick Wiseman, that began in 1974.
Annis was in a relationship with photographer Patrick Wiseman that began in 1974, raising three children, Charlotte, Taran, and Andreas, all of whom were given their father's surname. Annis began a relationship with Hamlet co-star Ralph Fiennes in 1995, ending her 23-year relationship with Wiseman in 1997, with Fiennes in turn divorcing his wife of four years, Alex Kingston. Annis is said to have "apologised to Wiseman" over their parting.