Hao Wu (biochemist) dating history

Hao Wu (biochemist) is a member of the following lists: Cornell University faculty, Purdue University alumni and Harvard Medical School faculty.

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Hao Wu (Chinese: 吴皓; pinyin: Wú Hào) is a Chinese American biochemist and structural biologist. She is the Asa and Patricia Springer Professor of Structural Biology in the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School, and a Senior Investigator in the Program in Cellular and Molecular Medicine at Boston Children’s Hospital. Her work focuses on molecular mechanisms of signal transduction in cell death and inflammation in innate immunity. She discovered large, higher-order protein assemblies involved in cell death and immune signaling - structures that, unlike traditional protein complexes, form filaments or circular oligomers and often lack fixed stoichiometry. These assemblies illuminate molecular mechanisms of proximity-driven enzyme activation, threshold behavior, signal amplification, noise reduction, and spatiotemporal regulation of signal transduction. They establish a new paradigm in signaling, and reveal mechanistic links to phase separation and biomolecular condensates. Together with Jon Kagan, she later dubbed these structures as supramolecular organizing centers (SMOCs).