1929 - 2019
Irwin Fridovich American Biologist
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Irwin Fridovich is a member of the following lists: American Jews, 1929 births and Duke University alumni.
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Details
| First Name |
Irwin
|
| Last Name |
Fridovich
|
| Birthday |
2nd August, 1929
|
| Birthplace |
New York City
|
| Died |
2nd November, 2019
|
| Zodiac Sign |
Leo
|
| Nationality |
American
|
| Occupation |
Biologist
|
Irwin Fridovich (August 2, 1929 – November 2, 2019) was an American biochemist who, together with his graduate student Joe M. McCord, discovered the enzymatic activity of copper-zinc superoxide dismutase (SOD),—to protect organisms from the toxic effects of superoxide free radicals formed as a byproduct of normal oxygen metabolism. Subsequently, Fridovich's research group also discovered the manganese-containing and the iron-containing SODs from E coli and the mitochondrial MnSOD (SOD2), now known to be an essential mammalian protein. He spent the rest of his career studying the biochemical mechanisms of SOD and of biological superoxide toxicity, using bacteria as model systems. Fridovich was also Professor Emeritus of Biochemistry at Duke University.
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