1981 - 1999
Jesse Gelsinger
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Jesse Gelsinger is a member of the following lists: 1981 births, 1999 deaths and Medical ethics.
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Details
| Birthday |
18th June, 1981
|
| Died |
17th September, 1999
|
| Zodiac Sign |
Gemini
|
Jesse Gelsinger (June 18, 1981 – September 17, 1999) was the first person publicly identified as having died in a clinical trial for gene therapy. Gelsinger suffered from ornithine transcarbamylase deficiency, an X-linked genetic disease of the liver, the symptoms of which include an inability to metabolize ammonia – a byproduct of protein breakdown. The disease is usually fatal at birth, but Gelsinger had a milder form of the disease, in which the ornithine transcarbamylase gene is mutated in only part of the patient's cells, a condition known as somatic mosaicism. As his deficiency was partial, Gelsinger managed to survive on a restricted diet and special medications.
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