1925 - 1983
Margaret Oakley Dayhoff American Biologist
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Margaret Oakley Dayhoff is a member of the following lists: New York University alumni, Columbia University alumni and 1925 births.
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Details
| First Name |
Margaret
|
| Middle Name |
Oakley
|
| Last Name |
Dayhoff
|
| Birthday |
11th March, 1925
|
| Birthplace |
Philadelphia
|
| Died |
5th February, 1983
|
| Place of Death |
Silver Spring, Maryland
|
| Zodiac Sign |
Pisces
|
| Nationality |
American
|
| Occupation |
Biologist
|
Margaret Belle (Oakley) Dayhoff (March 11, 1925 – February 5, 1983) was an American physical chemist and a pioneer in the field of bioinformatics. Dayhoff was a professor at Georgetown University Medical Center and a noted research biochemist at the National Biomedical Research Foundation (NBRF) where she pioneered the application of mathematics and computational methods to the field of biochemistry.
She dedicated her career to applying the evolving computational technologies to support advances in biology and medicine, most notably the creation of protein and nucleic acid databases and tools to interrogate the databases.
She originated one of the first substitution matrices, point accepted mutations (PAM). The one-letter code used for amino acids was developed by her, reflecting an attempt to reduce the size of the data files used to describe amino acid sequences in an era of punch-card computing.
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