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Opossunoquonuske is a member of the following lists: Native American leaders, People from Chesterfield County, Virginia and People from colonial Virginia.
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Opossunoquonuske (variant forms: Oppussoquionuske or Opposunoquonuske) (birthdate unknown – 1610) was a Weroansqua of an Appomattoc town near the mouth of the Appomattox River. Weroansqua (or Weroance) is an Algonquian word meaning leader or commander among the Powhatan confederacy of Virginia coast and Chesapeake Bay region. She was known as the queen of Appamatuck. The community she led was large enough to provide an estimated twenty warriors to the Powhatan Confederacy.
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