| Planes: Fire & Rescue | 2014 | Concierge (voice, as René Auberjonois) | Movie |
| The Librarians | 2014 | Mr. McGuire | TV Show |
| Madam Secretary | 2014 | Walter Nowack / Walter | TV Show |
| The Tom and Jerry Show | 2014 | Butler | TV Show |
| Wander Over Yonder | 2013 | Maurice | TV Show |
| Masters of Sex | 2013 | Dr. George Papanikolaou | TV Show |
| Avengers Assemble | 2013 | Ebony Maw / World Leader #1 | TV Show |
| Evermore | 2013 | Grandpa | Short Film |
| Ben 10 Omniverse 2 | 2013 | Azmuth (voice) | Unknown |
| 1600 Penn | 2012 | Winslow Hannum / Winslow | TV Show |
| Ben 10: Omniverse | 2012 | Azmuth / Additional Voices / Galvan Security Officer | TV Show |
| Dan Vs. | 2011 | Chef Purée | TV Show |
| The Looney Tunes Show | 2011 | Pepé Le Pew | TV Show |
| Uncharted 3: Drake's Deception | 2011 | Karl Schäfer (Multiplayer) (voice) | Unknown |
| Fallout: New Vegas | 2010 | Mr. House (voice) | Unknown |
| Young Justice | 2010 | Mark Desmond / Blockbuster | TV Show |
| BlackBoxTV | 2010 | Rudy | TV Show |
| Pound Puppies | 2010 | McLeish / Cat Narrator / Professor Schmierkankle | TV Show |
| Warehouse 13 | 2009 | Hugo Miller | TV Show |
| Bored to Death | 2009 | Henry Stevenson | TV Show |
| The Good Wife | 2009 | Coroner Claypool | TV Show |
| Archer | 2009 | Mannfred / Cardinal Giancarlo Morelli | TV Show |
| Uncharted 2: Among Thieves | 2009 | Karl Schäfer (voice) | Unknown |
| Star Trek Online | 2008 | Odo (voice) | Unknown |
| Random! Cartoons | 2007 | Hornswiggle | TV Show |
| Saving Grace | 2007 | Father Patrick Murphy | TV Show |
| Pirates of the Caribbean: At World's End | 2007 | Angler (voice) | Unknown |
| The Replacements | 2006 | Abraslam Lincoln | TV Show |
| Geppetto's Secret | 2005 | Mr. Sneap (voice) | Movie |
| Avatar: The Last Airbender | 2005 | Mechanist / Additional Voices / Gan Jin Leader | TV Show |
| Criminal Minds | 2005 | Colonel Ron Massey | TV Show |
| Grey's Anatomy | 2005 | Neil Sheridan | TV Show |
| It's Always Sunny in Philadelphia | 2005 | Dr. Larry Meyers | TV Show |
| Eulogy | 2004 | Parson Banke | Movie |
| Boston Legal | 2004 | Paul Lewiston | TV Show |
| Winx Club | 2004 | Saladin | TV Show |
| Duck Dodgers | 2003 | McChirpy | TV Show |
| NCIS | 2003 | Dr. Felix Blackwell | TV Show |
| Xiaolin Showdown | 2003 | Master Fung / Narrator | TV Show |
| Legacy of Kain: Defiance | 2003 | Janos Audron / Hylden Lord (voice) | Unknown |
| Neko no ongaeshi | 2002 | Natori (English version, voice) | Movie |
| Blood Omen II: Legacy of Kain | 2002 | Janos Audron / The Beast (voice, as René Aubergenois) | Unknown |
| Command & Conquer: Renegade | 2002 | Dr. Ignatio Mobius (voice) | Unknown |
| Dan Dare: Pilot of the Future | 2002 | Kuffka | TV Show |
| New Legends | 2002 | Topo / Kang (voice) | Unknown |
| Burning Down the House | 2001 | Pierre | Movie |
| The Princess Diaries | 2001 | Philippe Renaldi (voice, uncredited) | Movie |
| House of Mouse | 2001 | Chef Louis | TV Show |
| Justice League | 2001 | Galius Zed / Kanjar-Ro / Guardian of Oa / ... | TV Show |
| Star Trek: Enterprise | 2001 | Ezral | TV Show |
| The Legend of Tarzan | 2001 | Renard Dumont | TV Show |
| The Mummy: Secrets of the Medjai | 2001 | Scarab | TV Show |
| Legacy of Kain: Soul Reaver II | 2001 | Janos Audron (voice) | Unknown |
| The Patriot | 2000 | Reverend Oliver | Movie |
| We All Fall Down | 2000 | Tim | Movie |
| Sally Hemings: An American Scandal | 2000 | James Callender | TV Show |
| The Secret Adventures of Jules Verne | 2000 | Cavois | TV Show |
| Star Trek: Deep Space Nine - The Fallen | 2000 | Odo (voice) | Unknown |
| Inspector Gadget | 1999 | Artemus Bradford (as René Auberjonois) | Movie |
| Family Guy | 1999 | Odo | TV Show |
| Judging Amy | 1999 | Judge Jackson Keeler | TV Show |
| Xyber 9: New Dawn | 1999 | Xyber 9 | TV Show |
| Gabriel Knight 3: Blood of the Sacred, Blood of the Damned | 1999 | Taxi Driver / Bigout (voice) | Unknown |
| The Wild Thornberrys | 1998 | Merrick Dash | TV Show |
| Cats Don't Dance | 1997 | Flanigan (voice) | Movie |
| Los Locos | 1997 | Presidente | Movie |
| Snide and Prejudice | 1997 | Dr. Sam Cohen | Movie |
| Extreme Ghostbusters | 1997 | College Professor | TV Show |
| Men in Black: The Series | 1997 | Quintoon | TV Show |
| Stargate SG-1 | 1997 | Alar | TV Show |
| The Practice | 1997 | Judge F. Mantz | TV Show |
| The Wonderful World of Disney | 1997 | Prof. Buonragazzo | TV Show |
| Adventures from the Book of Virtues | 1996 | | TV Show |
| Bruno the Kid | 1996 | Leonard DaLinguini | TV Show |
| Captain Simian & The Space Monkeys | 1996 | The Gardener | TV Show |
| Jumanji | 1996 | | TV Show |
| Nash Bridges | 1996 | Hagen Bridges | TV Show |
| Poltergeist: The Legacy | 1996 | Milo Javits | TV Show |
| Richie Rich | 1996 | Chef Pierre / Professor Keenbean / Mr. Rich | TV Show |
| The Burning Zone | 1996 | Dr. Dicketts | TV Show |
| The Great War: 1914-1918 | 1996 | Mustafa Kemal Ataturk / Georg Ernst Hinzpeter / Jean Jaures / ... | TV Show |
| Tracey Takes On... | 1996 | William Catesby-Jones | TV Show |
| Star Trek: Deep Space Nine - Harbinger | 1996 | Odo (voice) | Unknown |
| Batman Forever | 1995 | Dr. Burton | Movie |
| The Outer Limits | 1995 | Dlavan | TV Show |
| The Savage Dragon | 1995 | Horde / Miles Legion | TV Show |
| Aladdin | 1994 | Nefir Hasenuf | TV Show |
| Chicago Hope | 1994 | Dr. Walter Kerry | TV Show |
| The Ballad of Little Jo | 1993 | Streight Hollander | Movie |
| Bonkers | 1993 | | TV Show |
| Frasier | 1993 | Dr. William Tewksbury / Professor William Tewksbury | TV Show |
| Marsupilami | 1993 | Chef Louie | TV Show |
| Mighty Max | 1993 | Arachnoid / Dr. Stanley Kirby / Nadja | TV Show |
| Star Trek: Deep Space Nine | 1993 | Constable Odo / Douglas Pabst / Curzon Dax | TV Show |
| The Player | 1992 | Rene Auberjonois | Movie |
| Ned Blessing: The True Story of My Life | 1992 | Marquis | TV Movie |
| The Sands of Time | 1992 | | TV Movie |
| Lucky Luke | 1992 | Mr. Edgar Rockbottom / Mendez | TV Show |
| Batman: The Animated Series | 1992 | Dr. March | TV Show |
| The Little Mermaid | 1992 | Chef Louie | TV Show |
| Wild Card | 1992 | Jake Spence | TV Movie |
| Absolute Strangers | 1991 | Quinn | TV Movie |
| Ashenden | 1991 | John Quincy Harrington | TV Show |
| Civil Wars | 1991 | Eugene Wilkenson | TV Show |
| The Pirates of Dark Water | 1991 | Kangent | TV Show |
| Darkwing Duck | 1991 | Venerable One / Curator | TV Show |
| Eerie, Indiana | 1991 | The Donald | TV Show |
| Rugrats | 1990 | Jonathan | TV Show |
| Tom & Jerry Kids Show | 1990 | | TV Show |
| The Feud | 1990 | Reverton | Movie |
| Timeless Tales from Hallmark | 1990 | | TV Show |
| Little Nemo: Adventures in Slumberland | 1989 | Professor Genius (voice) | Movie |
| The Little Mermaid | 1989 | Louis (voice, as René Auberjonois) | Movie |
| A Connecticut Yankee in King Arthur's Court | 1989 | Merlin | TV Movie |
| Billy the Kid | 1989 | Tunstall's Cousin | TV Movie |
| Doogie Howser, M.D. | 1989 | Einstein | TV Show |
| The Further Adventures of SuperTed | 1989 | Additional Voices | TV Show |
| Billy the Kid | 1989 | Additional Voices (voice) | TV Show |
| Police Academy 5: Assignment: Miami Beach | 1988 | Tony | Movie |
| Longarm | 1988 | Gov. Lew Wallace | TV Movie |
| A Pup Named Scooby-Doo | 1988 | Boris Rougefort | TV Show |
| Fantastic Max | 1988 | Additional Voices | TV Show |
| Superman | 1988 | General Zod | TV Show |
| The Completely Mental Misadventures of Ed Grimley | 1988 | Additional Voices | TV Show |
| My Best Friend Is a Vampire | 1987 | Modoc | Movie |
| Walker | 1987 | Major Siegfried Hennington | Movie |
| DuckTales | 1987 | Dr. Nogood | TV Show |
| Teenage Mutant Ninja Turtles | 1987 | Professor Chumley | TV Show |
| American Experience | 1987 | Alexander Hamilton | TV Show |
| 3:15 | 1986 | Horner | Movie |
| A Smoky Mountain Christmas | 1986 | Ned | TV Movie |
| Blacke's Magic | 1986 | Arthur Pym | TV Show |
| The New Adventures of Jonny Quest | 1986 | Additional Voices | TV Show |
| L.A. Law | 1986 | Kevin Richardson | TV Show |
| Matlock | 1986 | Councilman Leo Brodsky / Doug Michaels | TV Show |
| Pound Puppies | 1986 | Poodle / Pierre | TV Show |
| Wildfire | 1986 | Alvinar | TV Show |
| American Masters | 1985 | Fortunato (segment "The Cask of Amontillado") | TV Show |
| Punky Brewster | 1985 | Additional voices (voice) | TV Show |
| The Booth | 1985 | | TV Movie |
| The Greatest Adventure: Stories from the Bible | 1985 | | TV Show |
| Challenge of the GoBots | 1984 | Dr. Zebediah Braxis / Dr. Braxis | TV Show |
| Murder, She Wrote | 1984 | Homicide Captain Walker Thorn / Prof. Harry Papasian | TV Show |
| Snorks | 1984 | Dr. Strangesnork / Additional Voices | TV Show |
| The New Scooby-Doo Mysteries | 1984 | Additional Voices | TV Show |
| Teenage Tease | 1983 | Arthur, The Egg | Movie |
| Benson: The U.S. Goes to Market | 1983 | Clayton Runnymede Endicott III | Movie |
| The Last Unicorn | 1982 | The Skull (voice) | Movie |
| The Smurfs Christmas Special | 1982 | Stranger (voice) | TV Movie |
| Faerie Tale Theatre | 1982 | King Boris / King Ulrich | TV Show |
| The Kid from Nowhere | 1982 | Howard | TV Movie |
| The Smurfs | 1981 | Additional Voices | TV Show |
| Where the Buffalo Roam | 1980 | Harris (as René Auberjonois) | Movie |
| More Wild Wild West | 1980 | Capt. Sir David Edney | TV Movie |
| Beyond Westworld | 1980 | Power | TV Show |
| Tenspeed and Brown Shoe | 1980 | Marty Boxx | TV Show |
| The Fonz and the Happy Days Gang | 1980 | Additional Voices | TV Show |
| The Righteous Apples | 1980 | Dr. Danvers | TV Show |
| Scalpels | 1980 | Dr. Carl Jerrett | TV Movie |
| The Wild Wild West Revisited | 1979 | Capt. Sir David Edney | TV Movie |
| Benson | 1979 | Clayton Runnymede Endicott III | TV Show |
| Hart to Hart | 1979 | Donald Springfield | TV Show |
| Mrs. Columbo | 1979 | Bradlee / Monsieur Gerard | TV Show |
| CBS Library | 1979 | Ichabod Crane (segment "The Legend of Sleepy Hollow") | TV Show |
| Stockard Channing in Just Friends | 1979 | Roger | TV Show |
| Eyes of Laura Mars | 1978 | Donald Phelps | Movie |
| The Dark Secret of Harvest Home | 1978 | Jack Stump | TV Show |
| Richie Brockelman, Private Eye | 1978 | Shefland | TV Show |
| The Scooby-Doo Show | 1978 | | TV Show |
| The Rhinemann Exchange | 1977 | Dr. Eugene Lyons | TV Show |
| Man from Atlantis | 1977 | Havergal | TV Show |
| Rosetti and Ryan | 1977 | Jonathan | TV Show |
| King Kong | 1976 | Bagley | Movie |
| The Big Bus | 1976 | Father Kudos | Movie |
| Black Sheep Squadron | 1976 | Matthew Hooper | TV Show |
| Charlie's Angels | 1976 | Freddie Fortune / Terrence | TV Show |
| Delvecchio | 1976 | Harry Wilson | TV Show |
| Family | 1976 | Alvin | TV Show |
| The Bionic Woman | 1976 | Pierre Lambert | TV Show |
| Panache | 1976 | Panache | TV Movie |
| The TVTV Show | 1976 | News Editor | TV Movie |
| The Hindenburg | 1975 | Major Napier | Movie |
| Ellery Queen | 1975 | Marcel Fourchet | TV Show |
| Saturday Night Live | 1975 | Roberts (segment 'NBC Super Season') | TV Show |
| Starsky and Hutch | 1975 | The Baron | TV Show |
| The Jeffersons | 1975 | Inspector Keller | TV Show |
| Wonder Woman | 1975 | Kimball | TV Show |
| Rhoda | 1974 | Dr. John Fox | TV Show |
| The Rockford Files | 1974 | Masters | TV Show |
| The Lives of Benjamin Franklin | 1974 | | TV Show |
| Harry O | 1973 | Rabbit | TV Show |
| Super Friends | 1973 | Desaad | TV Show |
| Incident at Vichy | 1973 | Monceau, An Actor | TV Movie |
| Shirts/Skins | 1973 | Sidney Krebs | TV Movie |
| Images | 1972 | Hugh | Movie |
| Pete 'n' Tillie | 1972 | Jimmy Twitchell (as René Auberjonois) | Movie |
| The Bob Newhart Show | 1972 | Alan Durocher | TV Show |
| The Rookies | 1972 | Ron Kelly | TV Show |
| McCabe & Mrs. Miller | 1971 | Sheehan | Movie |
| The Birdmen | 1971 | Halden Brevik / Olav Volda | TV Movie |
| Great Performances | 1971 | Edgar | TV Show |
| McMillan & Wife | 1971 | Andre Stryker | TV Show |
| Brewster McCloud | 1970 | The Lecturer | Movie |
| MASH | 1970 | Father John Mulcahy | Movie |
| Love, American Style | 1969 | George (segment "Love and the Spaced Out Chick") | TV Show |
| Night Gallery | 1969 | William Sharsted (segment "Camera Obscura") | TV Show |
| Petulia | 1968 | Fred Six (uncredited) | Movie |
| Mod Squad | 1968 | Nelson Farraday / Endicott Farraday | TV Show |
| Lilith | 1964 | Howie (uncredited) | Movie |
| NET Playhouse | 1964 | George Washington / Ofoeti | TV Show |
| The Jetsons | 1962 | | TV Show |
